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Free ACLS sample questions

Real questions from the Advanced Cardiac Life Support practice bank, with the correct answer and an explanation for each one. No junk, no filler.

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Showing 9 of 19 free sample questions.

Question 1Choose one

A 68-year-old male with a history of congestive heart failure is successfully resuscitated from ventricular fibrillation. Post-ROSC, his blood pressure is 80/50 mmHg, heart rate is 110 bpm, and he is not following commands. Continuous waveform capnography shows an ETCO2 of 25 mmHg. Which intervention is the most critical immediate priority to improve neurologic outcomes?

Question 2Choose 2

During a cardiac arrest resuscitation, the team leader notes that the chest compression fraction (CCF) for the last cycle was 55%. What TWO actions should the team leader immediately implement to address this? (Select TWO)

Question 3Choose one

A patient with a regular, wide-complex tachycardia at a rate of 180/min becomes acutely hypotensive with a BP of 70/40 mmHg and shows signs of poor perfusion. The team prepares for synchronized cardioversion. What is the most common and dangerous error when delivering a synchronized shock?

Question 4Choose one

True or False: According to the 2020 AHA ACLS guidelines, routine administration of sodium bicarbonate to counteract acidosis during a typical cardiac arrest is strongly recommended.

Question 5Choose one

A 55-year-old female presents with symptomatic bradycardia at a rate of 40/min. She is diaphoretic and has a BP of 88/50 mmHg. The monitor shows a third-degree AV block. Two doses of atropine 1 mg IV have been administered with no improvement. What is the next most appropriate intervention?

Question 6Choose one

A hospital's resuscitation quality improvement committee is reviewing data from recent cardiac arrest events. They want to assess the effectiveness of chest compressions using quantitative waveform capnography. Which ETCO2 value is the minimum threshold that indicates high-quality CPR?

Question 7Choose one

A patient arrives at the emergency department with symptoms suggestive of an acute stroke. The initial non-contrast CT scan of the head is negative for hemorrhage. The patient meets all other criteria for fibrinolytic therapy. According to the ACLS Suspected Stroke Algorithm, fibrinolytic therapy (tPA) should be administered within what timeframe from the onset of symptoms?

Question 8Choose one

**Case Study** A 72-year-old male is brought to the ED with a chief complaint of severe, crushing substernal chest pain that began 45 minutes ago. He has a history of hypertension and type 2 diabetes. His initial vital signs are BP 160/95 mmHg, HR 95 bpm, RR 22/min, and SpO2 96% on room air. He is given 324 mg of aspirin to chew. A 12-lead ECG is immediately obtained and shows 4 mm ST-segment elevation in leads V2, V3, and V4. The facility has a cardiac catheterization lab that is currently available and staffed. The estimated door-to-balloon time is 60 minutes. Which of the following is the most appropriate next step in the management of this patient?

Question 9Choose one

A patient in cardiac arrest has been intubated with an endotracheal tube. The ventilator is set to deliver 10 breaths per minute. During CPR, chest compressions should be performed at a rate of 100-120 per minute and be ______ with ventilations.

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